Isotopically Labeled Compounds
Medchemexpress LLC Glyburide-d3 | 1219803-02-7 | C23H25D3ClN3O5S | 5 MG
Glyburide-d3 is the deuterium labeled Glibenclamide. Glibenclamide (Glyburide) is an orally active ATP-sensitive K+ channel (KATP) inhibitor used for diabetes and obesity research. It inhibits P-glycoprotein, directly binds and blocks the SUR1 subunits of KATP, and inhibits the cystic fibrosis transmembrane conductance regulator protein (CFTR). It interferes with mitochondrial bioenergetics by inducing changes on membrane ion permeability and can induce autophagy.
- Used as a tracer.
- Used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Inhibits P-glycoprotein.
- Blocks SUR1 subunits of KATP.
- Inhibits the cystic fibrosis transmembrane conductance regulator protein (CFTR).
- Interferes with mitochondrial bioenergetics.
- Induces autophagy.
Cayman Chemical Darifenacin-d4, Purity: ≥99% deuterated forms (d1-d4), CAS: 1189701-43-6, 10 mg
An internal standard for the quantification of darifenacin by GC- or LC-MS
Medchemexpress LLC Istradefylline-13C,d3 | 2749234-46-4 | 98.3% | 388.44 | 10 MG
Istradefylline-13C,d3 is the 13C- and deuterium labeled version of Istradefylline, a highly potent, selective, and orally active adenosine A2A receptor antagonist with a Ki of 2.2 nM. It has been studied in experimental models of Parkinson's disease. This compound is intended for research use only and can be used for quantitative analysis.
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Medchemexpress LLC Pentoxifylline-d6 | 1185878-98-1 | 99.0% | 284.34 g/mol | C13H12D6N4O3 | 10 MG
Pentoxifylline-d6 is the deuterium-labeled analog of pentoxifylline provided as a research standard for analytical and tracer studies. It is intended for use as an internal standard in mass spectrometry, quantitative analysis, and pharmacokinetic or metabolic research; for laboratory research use only.
- Deuterium-labeled (d6) internal standard for mass spectrometry.
- High purity: 99.0%.
- Molecular formula C13H12D6N4O3; molecular weight 284.34 g/mol.
- CAS number 1185878-98-1 for unambiguous identification.
- Appearance: white to off-white solid suitable for analytical handling.
- Available as a 10 mg research quantity.
Medchemexpress LLC Succinimide-15N | 32807-36-6 | MFCD00084242 | 99.0% | 100.08 | C4H5(15)NO2 | 10 MG
Succinimide-15N is the 15N-labeled form of succinimide supplied as a powder for use as an isotope-labeled reagent in mass spectrometry, tracer studies, and biochemical analyses. It provides high isotopic enrichment and is intended for analytical workflows requiring stable nitrogen labeling.
- 15N-labeled succinimide for tracer and mass spectrometry applications.
- High isotopic and chemical purity (≥99.0%).
- Available in small research sizes such as 5 mg, 10 mg, and 25 mg.
- Powder form with recommended frozen or cold storage to maintain stability.
- CAS number: 32807-36-6.
Medchemexpress LLC Propofol-d17 β-D-glucuronide | 1683581-05-6 | 98.0% | 371.50 g/mol | C18H9D17O7 | 1 MG
Propofol-d17 β-D-glucuronide is a deuterium-labeled internal standard of propofol β-D-glucuronide suitable for use as a tracer or quantitative reference in NMR, GC-MS, and LC-MS analyses. It is supplied as a high-purity isotopologue for metabolite quantitation and method development.
- Deuterium-labeled propofol β-D-glucuronide for use as an internal standard
- High purity: 98.0%
- Available in small quantities including 1 mg
- Soluble in ethanol, DMF, and DMSO at ≥ 30 mg/mL
- Powder: store at -20°C; in solvent: -80°C (6 months) or -20°C (1 month)
- Suitable for NMR, GC-MS, and LC-MS quantitative analysis
Medchemexpress LLC Zanubrutinib-d5 | 00-00-0 | 99.0% | 476.58 g/mol | C27H24D5N5O3 | 1 MG
Zanubrutinib-d5 is a deuterium-labeled analogue of zanubrutinib intended for research use as a tracer or internal standard in quantitative analyses by NMR, GC-MS, and LC-MS. It is supplied as a solid for laboratory studies and therapeutic drug monitoring method development.
- Deuterium-labeled internal standard for quantitative analysis
- Purity: 99.0%
- Molecular formula: C27H24D5N5O3; molecular weight: 476.58 g/mol
- Appearance: white to off-white solid
- Solubility: DMSO 30 mg/mL; may require ultrasonic and warming
- Storage: powder -20°C (3 years) or 4°C (2 years); in solvent -80°C (6 months)
- Packaged in small-mass units suitable for analytical standards (1 mg available)
![Revvity Health Sciences Inc Deoxythymidine 5'-Triphosphate, [Methyl-3H]-, EtOH Sol, Tetrasodium Salt, Specific Activity: 70-90 Ci (2.59-3.33 TBq)/mmol, 5 mCi (185 MBq)](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502809325.jpg-250.jpg)
Revvity Health Sciences Inc Deoxythymidine 5'-Triphosphate, [Methyl-3H]-, EtOH Sol, Tetrasodium Salt, Specific Activity: 70-90 Ci (2.59-3.33 TBq)/mmol, 5 mCi (185 MBq)
Deoxythymidine 5'-Triphosphate, [Methyl-3H]-, EtOH Sol, Tetrasodium Salt, Specific Activity: 70-90 Ci (2.59-3.33 TBq)/mmol, 5 mCi (185 MBq)
Medchemexpress LLC N,N-dimethyl-4-(phenyldiazenyl)aniline-d5 | 1398109-08-4 | MFCD22565739 | 99.0% | 230.32 g/mol | C14H10D5N3 | 25 MG
Methyl yellow-d5 (N,N-dimethyl-4-(phenyldiazenyl)aniline-d5) is the deuterium-labeled isotopologue of methyl yellow supplied as a high-purity analytical reference standard. It is intended for use as a tracer or internal standard in mass spectrometry and other analytical workflows, and is provided with high isotopic enrichment and defined storage recommendations.
Medchemexpress LLC (±)12(13)Epoxy-9Z-octadecenoic-9,10,12,13-d4 acid | 17966-13-1 | 99.0% | 300.47 | 25 UG
(±)12(13)-EpOME-d4 is a deuterium labeled compound designed for research use. It can serve as a tracer and an internal standard in quantitative analysis methods such as NMR, GC-MS, or LC-MS. Deuteration may influence the pharmacokinetic and metabolic profiles of drugs.
- Used as a tracer
- Functions as an internal standard for quantitative analysis
- Applicable in NMR, GC-MS, or LC-MS
- Deuterium labeled compound
![Revvity Health Sciences Inc dCTP, [α-<sup>32</sup>P]- 3000Ci/mmol 10mCi/ml EasyTide, 1 mCi](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502809218.jpg-250.jpg)
Revvity Health Sciences Inc dCTP, [α-32P]- 3000Ci/mmol 10mCi/ml EasyTide, 1 mCi
dCTP, [α-32P]- 3000Ci/mmol 10mCi/ml EasyTide, 1 mCi
Medchemexpress LLC Uridine-13C,15N2 | 369656-75-7 | 1 MG
Uridine-13C,15N2 is a 13C- and 15N-labeled Uridine. It is intended for research use only. This compound can be used as a tracer and as an internal standard for quantitative analysis. Stable heavy isotopes of hydrogen, carbon, and other elements are incorporated into drug molecules as tracers for quantitation during drug development. Deuteration has gained attention due to its potential to affect pharmacokinetic and metabolic profiles of drugs.
- Can be utilized as a tracer.
- Serves as an internal standard for quantitative analysis using techniques such as NMR, GC-MS, or LC-MS.
Medchemexpress LLC Hexanedioic acid dimethyl ester-d8 | 52089-64-2 | 10mg
Dimethyl adipate-d8 (Hexanedioic acid dimethyl ester-d8) is the deuterium labeled Dimethyl adipate (HY-W015301) Dimethyl adipate is an aliphatic dicarboxylate compound Dimethyl adipate is mainly used as a plasticizer and an intermediate in organic synthesis
Medchemexpress LLC Decanoic acid-d19 | 88170-22-3 | 98.4% | 191.38 | C10HD19O2 | 5 MG
Decanoic acid-d19 is the deuterium-labeled form of decanoic (capric) acid used as an isotope-labeled standard and tracer in analytical, metabolic, and pharmacokinetic research. It is a deuterated fatty acid reported to be brain-penetrant and a non-competitive AMPA receptor inhibitor; the material is supplied for laboratory use with batch documentation available.
- Deuterium-labeled (d19) analog for isotope tracing.
- High reported purity: 98.4%.
- Molecular formula C10HD19O2; molecular weight 191.38.
- Supplied in small pack sizes suitable for analytical work.
- Provided with certificate of analysis and safety data sheet.
- Suitable for metabolic, pharmacokinetic, and tracer studies.
- Useful as an internal standard for mass spectrometry.
Medchemexpress LLC Pimobendan-d3 | 74150-27-9 | 99.4% | 337.39 | C19H15D3N4O2 | 10 MG
Pimobendan-d3 is a deuterium-labeled isotopologue of pimobendan supplied as a stable-isotope reference standard for analytical and research use. It is intended for LC-MS internal standard and tracer studies and shares the pharmacological annotation of the parent compound (pimobendan), a selective PDE3 inhibitor (IC50 = 0.32 μM).
- Deuterium-labeled internal standard for LC-MS and tracer studies.
- High purity (99.43%).
- Molecular weight 337.39 Da.
- CAS number 74150-27-9 for unambiguous identification.
- Available in small vial sizes, including 10 mg, for analytical workflows.